Today's topic will touch on how to use NAD+ precursor to improve one particular type of eczema, that is caused by adrenal fatigue.
Adrenal fatigue and eczema are two conditions that often go hand in hand. Adrenal fatigue is a state of exhaustion caused by chronic stress, which can lead to a weakened immune system and an overactive inflammatory response. This can contribute to the development or exacerbation of eczema, a skin condition characterized by red, itchy, and inflamed patches.
If you're struggling with eczema that is caused by adrenal fatigue, there's hope. One promising approach is to support the body's natural production of NAD+, a coenzyme that plays a critical role in energy production and cellular repair.
Here's why. NAD+ decline have a significant impact on the production of a very important hormone by the adrenal gland, and that is cortisol. Cortisol is a hormone that plays a crucial role in the body's stress response system, helping to regulate blood sugar levels, blood pressure, and immune function.
The adrenal gland produces cortisol from cholesterol through a complex process involving several biochemical pathways. One of these pathways involves the conversion of pregnenolone to progesterone. This is further converted to cortisol through a series of enzymatic reactions.
However, this process requires a constant supply of energy in the form of NAD+ or NADP+ as a cofactor in the conversion process, which occurs at the mitochondria and endoplasmic reticulum of the adrenal cells. If you understand this concept, then you would have learnt one of the most significant reason why adrenal fatigue occurs.
(diagram cited from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365799/)
NAD+ levels naturally decline as we age and in response to stress, which can impair cellular function and contribute to a wide range of health issues, including adrenal fatigue and eczema. However, research has shown that supplementing with NAD+ precursors, can help to restore NAD+ levels and improve cellular function.
Additionally, NAD+ precursors, such as NMN, has been shown to activate sirtuins, a family of proteins that play a critical role in regulating cellular metabolism, inflammation, and DNA repair. By activating sirtuins, it can help to restore back the level of cortisol and thus reduce the 'flaming' overactive immune system.
I know right....it is very counterintuitive. Mainstream topic has 'bad mouth' so much about cortisol that now everyone thinks that cortisol is bad. Yes in a way when it is elevated due to long term stress. But when the adrenal fatigue finally sets in, and they stop producing cortisol, another set of problem such as uncontrolled overactive immune system can arise. And one of the condition this leads to is...eczema.
If you're interested in using NAD+ precursors to support your adrenal and skin health, it's important to choose a high-quality supplement from a reputable manufacturer. Look for products that are third-party tested for purity and potency, and try it first before starting any new supplement regimen.
In summary, adrenal fatigue and eczema are complex conditions that are often intertwined. However, by supporting your body's natural production of NAD+ with the use of NAD+ precursors, you can potentially improve mitochondrial function, reduce inflammation, and support overall cellular health.